Scientific References
At Anova IRM, we work by the principles of translational medicine. Following this and our ethical code, we only apply and recommend the use of stem cells if there is a clear scientific rational for the specific case and disease. A rational can come from guide lines, clinical trials, pre-clinical trials or a strong scientific rational - always weighted against risk and safety associated. This is a list of literature relevant for our work at Anova IRM. Literature research for the latest scientific literature is done in every patient case. Therefore, the list is neither complete nor reflects our entire library and working principles.
References and Literature - Stem Cell Secretome
- Konala, Vijay Bhaskar Reddy, et al. "The current landscape of the mesenchymal stromal cell secretome: a new paradigm for cell-free regeneration." Cytotherapy 18.1 (2016): 13-24.
- Lopez-Verrilli, M. A., et al. "Mesenchymal stem cell-derived exosomes from different sources selectively promote neuritic outgrowth." Neuroscience 320 (2016): 129-139.
- Kim, Hyun Ok, Seong-Mi Choi, and Han-Soo Kim. "Mesenchymal stem cell-derived secretome and microvesicles as a cell-free therapeutics for neurodegenerative disorders." Tissue Engineering and Regenerative Medicine 10.3 (2013): 93-101.
- Rani, Sweta, et al. "Mesenchymal stem cell-derived extracellular vesicles: toward cell-free therapeutic applications." Molecular Therapy 23.5 (2015): 812-823.
- Zhang, Xiaoyan, et al. "Mesenchymal Stem Cell-Derived Extracellular Vesicles: Roles in Tumor Growth, Progression, and Drug Resistance." Stem Cells International 2017 (2017).
- omzikova, Marina O., and Albert A. Rizvanov. "Current Trends in Regenerative Medicine: From Cell to Cell-Free Therapy." BioNanoScience (2016): 1-6.
- Zhang, Bin, et al. "Focus on extracellular vesicles: Therapeutic potential of stem cell-derived extracellular Vesicles." International journal of molecular sciences 17.2 (2016): 174.
- Katsuda T. et al. (2013). Human adipose tissue-derived mesenchymal stem cells secrete functional neprilysin-bound exosomes. Scientific reports, 3, 1197.
- Pusic A. D. et al. (2014). IFNγ-stimulated dendritic cell exosomes as a potential therapeutic for remyelination. Journal of neuroimmunology, 266(1), 12-23.
- Maumus M, Jorgensen C, Noël D (2013) Mesenchymal stem cells in regenerative medicine applied to rheumatic diseases: Role of secretome and exosomes. Biochimie 95:2229–2234. doi: 10.1016/j.biochi.2013.04.017
- Drago D, Cossetti C, Iraci N, et al (2013) Biochimie The stem cell secretome and its role in brain repair. Biochimie 95:2271–2285. doi: 10.1016/j.biochi.2013.06.020
- Sevivas N, Teixeira FG, Portugal R, et al (2016) Mesenchymal Stem Cell Secretome: A Potential Tool for the Prevention of Muscle Degenerative Changes Associated With Chronic Rotator Cuff Tears. Am J Sports Med. doi: 10.1177/0363546516657827
- Hs K (2016) Mesenchymal Stem Cells vs . Mesenchymal Stem Cell Secretome for Rheumatoid Arthritis Treatment. 1:1–2.
- Maumus M, Jorgensen C, Noël D (2013) Mesenchymal stem cells in regenerative medicine applied to rheumatic diseases: Role of secretome and exosomes. Biochimie 95:2229–2234. doi: 10.1016/j.biochi.2013.04.017
- Kapur SK, Katz AJ (2013) Biochimie Review of the adipose derived stem cell secretome. Biochimie 95:2222–2228. doi: 10.1016/j.biochi.2013.06.001
- Ranganath SH, Levy O, Inamdar MS, Karp JM (2012) Harnessing the mesenchymal stem cell secretome for the treatment of cardiovascular disease. Cell Stem Cell 10:244–258. doi: 10.1016/j.stem.2012.02.005
- Tran C, Damaser MS (2015) Stem cells as drug delivery methods: Application of stem cell secretome for regeneration. Adv Drug Deliv Rev 82:1–11. doi: 10.1016/j.addr.2014.10.007
- Zimmerlin L, Park TS, Zambidis ET, et al (2013) Mesenchymal stem cell secretome and regenerative therapy after cancer. Biochimie 95:2235–2245. doi: 10.1016/j.biochi.2013.05.010
- Calamia V, Lourido L, Fernandez-Puente P, et al (2012) Secretome analysis of chondroitin sulfate-treated chondrocytes reveals its anti-angiogenic, anti-inflammatory and anti-catabolic properties. Arthritis Res Ther 14:R202. doi: 10.1186/ar4040
- Ranganath SH, Levy O, Inamdar MS, Karp JM (2012) Review Harnessing the Mesenchymal Stem Cell Secretome for the Treatment of Cardiovascular Disease. Stem Cell 10:244–258. doi: 10.1016/j.stem.2012.02.005
- Teixeira FG, Carvalho MM, Sousa N, Salgado AJ (2013) Mesenchymal stem cells secretome: A new paradigm for central nervous system regeneration? Cell Mol Life Sci 70:3871–3882. doi: 10.1007/s00018-013-1290-8
- Kapur SK, Katz AJ (2013) Review of the adipose derived stem cell secretome. Biochimie 95:2222–2228. doi: 10.1016/j.biochi.2013.06.001
- Chang C-P, Chio C-C, Cheong C-U, et al (2013) Hypoxic preconditioning enhances the therapeutic potential of the secretome from cultured human mesenchymal stem cells in experimental traumatic brain injury. Clin Sci (Lond) 124:165–76. doi: 10.1042/CS20120226
- Salgado AJ, Sousa JC, Costa BM, et al (2015) Mesenchymal stem cells secretome as a modulator of the neurogenic niche: basic insights and therapeutic opportunities. Front Cell Neurosci 9:1–18. doi: 10.3389/fncel.2015.00249
- Ahmed NE-MB, Murakami M, Hirose Y, Nakashima M (2016) Therapeutic Potential of Dental Pulp Stem Cell Secretome for Alzheimer’s Disease Treatment: An In Vitro Study. Stem Cells Int 2016:8102478. doi: 10.1155/2016/8102478
- Bhaskar V, Konala R, Mamidi MK, et al (2016) The current landscape of the mesenchymal stromal cell secretome : A new paradigm for cell-free regeneration. Cytotherapy 18:13–24. doi: 10.1016/j.jcyt.2015.10.008
- Malda J, Boere J, van de Lest C, et al (2016) Extracellular vesicles - new tool for joint repair and regeneration - IN PRESS. Nat Rev Rheumatol 12:243–249. doi: 10.1038/nrrheum.2015.170
- Lener T, Gimona M, Aigner L, et al (2015) Applying extracellular vesicles based therapeutics in clinical trials Á an ISEV position paper. 1:1–31.
- Dostert G, Mesure B, Menu P, Velot É (2017) How Do Mesenchymal Stem Cells Influence or Are Influenced by Microenvironment through Extracellular Vesicles Communication ? 5:1–7. doi: 10.3389/fcell.2017.00006
- Joshi P, Benussi L, Furlan R, et al (2015) Extracellular vesicles in Alzheimer’s disease: Friends or foes? focus on Aβ-vesicle interaction. Int. J. Mol. Sci. 16:4800–4813.
- Gao T, Guo W, Chen M, et al (2016) Extracellular Vesicles and Autophagy in Osteoarthritis.
- Katsuda T, Ochiya T (2015) Molecular signatures of mesenchymal stem cell-derived extracellular vesicle-mediated tissue repair. Stem Cell Res Ther 6:212. doi: 10.1186/s13287-015-0214-y
- Lener T, Gioma M, Aigner L, et al (2015) Applying extracellular vesicles based therapeutics in clinical trials - an ISEV position paper. J Extracell Vesicles 4:1–31. doi: 10.3402/jev.v4.30087
- Xu Y, Guo S, Wei C, et al (2016) The Comparison of Adipose Stem Cell and Placental Stem Cell in Secretion Characteristics and in Facial Antiaging.
- Buul GM Van, Villafuertes E, Bos PK, et al (2012) Mesenchymal stem cells secrete factors that inhibit in fl ammatory processes in short-term osteoarthritic synovium and cartilage explant culture. Osteoarthr Cartil 20:1186–1196. doi: 10.1016/j.joca.2012.06.003
- Baglio SR, Pegtel DM, Baldini N (2012) Mesenchymal stem cell secreted vesicles provide novel opportunities in ( stem ) cell-free therapy. 3:1–11. doi: 10.3389/fphys.2012.00359
- Anderson JD, Pham MT, Contreras Z, et al (2016) Mesenchymal stem cell-based therapy for ischemic stroke. Chinese Neurosurg J 2:36. doi: 10.1186/s41016-016-0053-4
- Biology C, Cell R, Eye N, Institutes N (2017) Bone Marrow-Derived Mesenchymal Stem Cells-Derived Exosomes Promote Survival of Retinal Ganglion Cells Through miRNA-Dependent Mechanisms. 1273–1285.
References and Literature - Bone Marrow Concentrate 'BMC'
- He Y, He W, Qin G, Luo J, Xiao M. Transplantation KCNMA1 modified bone marrow-mesenchymal stem cell therapy for diabetes mellitus-induced erectile dysfunction. Andrologia. 2014;46(5):479-486. doi:10.1111/and.12104.
- Mathiasen AB, Qayyum AA, Jørgensen E, et al. Bone marrow-derived mesenchymal stromal cell treatment in patients with severe ischaemic heart failure: a randomized placebo-controlled trial ({MSC}-{HF} trial). Eur Heart J. 2015;36(27):1744-1753. doi:10.1093/eurheartj/ehv136.
- Mathiasen AB, Qayyum AA, Jørgensen E, et al. Interventional cardiology Bone marrow-derived mesenchymal stromal cell treatment in patients with severe ischaemic heart failure?: a randomized placebo-controlled trial. 2015. doi:10.1093/eurheartj/ehv136.
- Liao H-T, Chen C-T. Osteogenic potential: Comparison between bone marrow and adipose-derived mesenchymal stem cells. World J Stem Cells. 2014;6(3):288-295. doi:10.4252/wjsc.v6.i3.288.
- Terai S, Ishikawa T, Omori K, et al. Improved liver function in patients with liver cirrhosis after autologous bone marrow cell infusion therapy. Stem Cells. 2006;24(10):2292-2298. doi:10.1634/stemcells.2005-0542.
- 2015_Cao_Spine-Journal_Bone-marrow-mesenchymal-stem-cells-slow-intervertebral-disc-degeneration-through-the-NF-?B-pathway.pdf.
- Zhao J, Zhang Q, Wang Y, Li Y. Uterine Infusion With Bone Marrow Mesenchymal Stem Cells Improves Endometrium Thickness in a Rat Model of Thin Endometrium. Reprod Sci. 2015;22(2):181-188. doi:10.1177/1933719114537715.
- Fekete N, Rojewski MT, Fürst D, et al. GMP-compliant isolation and large-scale expansion of bone marrow-derived MSC. PLoS One. 2012;7(8). doi:10.1371/journal.pone.0043255.
- Elman JS, Li M, Wang F, Gimble JM, Parekkadan B. A comparison of adipose and bone marrow-derived mesenchymal stromal cell secreted factors in the treatment of systemic inflammation. 2014:4-11.
- Li C, Wu X, Tong J, et al. Comparative analysis of human mesenchymal stem cells from bone marrow and adipose tissue under xeno-free conditions for cell therapy. Stem Cell Res Ther. 2015;6(1):55. doi:10.1186/s13287-015-0066-5.
- Books J, Sign R. Safety of Intracavernous Bone Marrow-Mononuclear Cells for Postrad ... Safety of Intracavernous Bone Marrow-Mononuclear Cells for Postradical Prostatectomy Erectile Dysfunction?: An Open Dose-Escalation Pilot Study Safety of Intracavernous Bone Marrow-Mon. 2017:2015-2017.
- Rinker TE, Hammoudi TM, Kemp ML, Lu H, Temenoff JS. Interactions between mesenchymal stem cells, adipocytes, and osteoblasts in a 3D tri-culture model of hyperglycemic conditions in the bone marrow microenvironment. Integr Biol (Camb). 2014;6(3):324-337. doi:10.1039/c3ib40194d.
- Al-sayegh H, Bashir J, Goodyear S, Freeman MD. A prospective multi-site registry study of a specific protocol of autologous bone marrow concentrate for the treatment of shoulder rotator cuff tears and osteoarthritis. 2015:269-276.
- Rager TM, Olson JK, Zhou Y, Wang Y, Besner GE. Exosomes secreted from bone marrow-derived mesenchymal stem cells protect the intestines from experimental necrotizing enterocolitis. J Pediatr Surg. 2016;51(6):942-947. doi:10.1016/j.jpedsurg.2016.02.061.
- Tate-oliver K, Alexander RW. Density Platelet-Rich Plasma or Bone Marrow.
- Tang K, Yan J, Shen Y, et al. Tracing type 1 diabetic Tibet miniature pig ? s bone marrow mesenchymal stem cells in vitro by magnetic resonance imaging. 2014;6:123-131. doi:10.1111/1753-0407.12084.
- Wang X, Mamillapalli R, Mutlu L, Du H, Taylor HS. Chemoattraction of bone marrow-derived stem cells towards human endometrial stromal cells is mediated by estradiol regulated CXCL12 and CXCR4 expression. Stem Cell Res. 2015;15(1):14-22. doi:10.1016/j.scr.2015.04.004.
- Rambaldi A, Capelli C, Domenghini M, et al. Human platelet lysate allows expansion and clinical grade production of mesenchymal stromal cells from small samples of bone marrow aspirates or marrow filter washouts. 2007:785-791. doi:10.1038/sj.bmt.1705798.
- Mushtaq M, Williams AR, Suncion VY, et al. Transendocardial Mesenchymal Stem Cells and Mononuclear Bone Marrow Cells for Ischemic Cardiomyopathy The TAC-HFT Randomized Trial. 2015;16960. doi:10.1001/jama.2013.282909.
- 2014 Autografting of bone marrow mesenchymal stem cells alleviates streptozotocin induced diabetes in miniature pigs.pdf.
- Program T, Marga- P, Kingdom U. Bone Marrow Therapies for Chronic Heart Dis- ease. 2015:1-12. doi:10.1002/stem.2080.
- Biology C, Cell R, Eye N, Institutes N, Infor- AS. Bone Marrow-Derived Mesenchymal Stem Cells-Derived Exosomes Promote Survival of Retinal Ganglion Cells Through miRNA-Dependent Mechanisms. 2017:1273-1285. doi:10.1002/sctm.12056.
- Jeong Y, Kyu H, Hwa H, Chan Y. Cellular Physiology and Biochemistr y Biochemistry Direct Comparison of Human Mesenchymal Stem Cells Derived from Adipose Tissues and Bone Marrow in Mediating Neovascularization in Response to Vascular Ischemia. Cell Physiol Biochem. 2007;20:867-876.
- Shutian S, Shaoping N, Xingxin W, et al. GW25-e3198 The combination of transforming growth factor ?1 and 5-azacytidine improve the differentiation effects of rat Bone marrow mesenchymal stem cells into cardiomyocytes. J Am Coll Cardiol. 2014;64(16):C21. doi:10.1016/j.jacc.2014.06.105.
- Narita T, Suzuki K. Bone marrow-derived mesenchymal stem cells for the treatment of heart failure. Heart Fail Rev. 2014:53-68. doi:10.1007/s10741-014-9435-x.
- Elman JS, Li M, Wang F, Gimble JM, Parekkadan B. A comparison of adipose and bone marrow-derived mesenchymal stromal cell secreted factors in the treatment of systemic inflammation. J Inflamm (Lond). 2014;11:1. doi:10.1186/1476-9255-11-1.
- Dong X, Zhu F, Liu Q, et al. Transplanted bone marrow mesenchymal stem cells protects myocardium by regulating 14-3-3 protein in a rat model of diabetic cardiomyopathy. 2014;7(7):3714-3723.
- Huang L, Wu W, Luo F. Umbilical Cord Mesenchymal Stromal Cell With Autologous Bone Marrow Cell Transplantation in Established Type 1 Diabetes?: A Pilot Randomized Controlled Open-Label Clinical Study to Assess Safety and Impact on Insulin Secretion. 2016:1-9. doi:10.2337/dc15-0171.
- Sanghi V, Sethi D, Harris KL, et al. International Journal of the Cardiovascular Academy Autologous bone marrow concentrate enriched in progenitor cells ? An adjuvant in the treatment of acute myocardial infarction. IJCAC. 2016. doi:10.1016/j.ijcac.2016.04.001.
- Leyh M, Seitz A, Dürselen L, et al. Subchondral bone influences chondrogenic differentiation and collagen production of human bone marrow-derived mesenchymal stem cells and articular chondrocytes. 2014:1-18. doi:10.1186/s13075-014-0453-9.
- Surgery M, Stomatological S, Material CP, et al. T ISSUE -S PECIFIC S TEM C ELLS Adiponectin Regulates Bone Marrow Mesenchymal Stem Cell Niche Through a Unique Signal Transduction Pathway?: An Approach for Treating Bone Disease in Diabetes. 2015:240-252.
- Li C, Wu X, Tong J, et al. Comparative analysis of human mesenchymal stem cells from bone marrow and adipose tissue under xeno-free conditions for cell therapy. Stem Cell Res Ther. 2015;6(1):55. doi:10.1186/s13287-015-0066-5.
- Mead B, Logan A, Berry M, Leadbeater W, Scheven BA. Paracrine-Mediated Neuroprotection and Neuritogenesis of Axotomised Retinal Ganglion Cells by Human Dental Pulp Stem Cells: Comparison with Human Bone Marrow and Adipose-Derived Mesenchymal Stem Cells. PLoS One. 2014;9(10):e109305. doi:10.1371/journal.pone.0109305.
- Cao C, Zou J, Liu X, Shapiro A. Bone marrow mesenchymal stem cells slow intervertebral disc degeneration through the NF- k B pathway. Spine J. 2015;15(3):530-538. doi:10.1016/j.spinee.2014.11.021.
- Li C, Wu X, Tong J, et al. Comparative analysis of human mesenchymal stem cells from bone marrow and adipose tissue under xeno-free conditions for cell therapy. ??? 2015. doi:10.1186/s13287-015-0066-5.
- Narita T, Suzuki K. Bone marrow-derived mesenchymal stem cells for the treatment of heart failure. 2015:53-68. doi:10.1007/s10741-014-9435-x.
- Heldman AW, DiFede DL, Fishman JE, et al. Transendocardial Mesenchymal Stem Cells and Mononuclear Bone Marrow Cells for Ischemic Cardiomyopathy. Jama. 2014;311(1):62. doi:10.1001/jama.2013.282909.
- Baglio SR, Rooijers K, Koppers-Lalic D, et al. Human bone marrow- and adipose-mesenchymal stem cells secrete exosomes enriched in distinctive miRNA and tRNA species. Stem Cell Res Ther. 2015;6(1):127. doi:10.1186/s13287-015-0116-z.
- Islam MN, Das SR, Emin MT, et al. Mitochondrial transfer from bone-marrow-derived stromal cells to pulmonary alveoli protects against acute lung injury. Nat Med. 2012;18(5):759-765. doi:10.1038/nm.2736.
- Baglio SR, Rooijers K, Koppers-Lalic D, et al. Human bone marrow- and adipose-mesenchymal stem cells secrete exosomes enriched in distinctive miRNA and tRNA species. Stem Cell Res Ther. 2015;6(1):127. doi:10.1186/s13287-015-0116-z.
- Bian S, Zhang L, Duan L, et al. Extracellular vesicles derived from human bone marrow mesenchymal stem cells promote angiogenesis in a rat myocardial infarction model. J Mol Med (Berl). 2014;92(4):387-397. doi:10.1007/s00109-013-1110-5.
- Shabbir A, Zisa D, Suzuki G, Lee T. Heart failure therapy mediated by the trophic activities of bone marrow mesenchymal stem cells: a noninvasive therapeutic regimen. Am J Physiol Heart Circ Physiol. 2009;296(6):H1888-H1897. doi:10.1152/ajpheart.00186.2009.
- Czubak PB, Bojarska-junak A, Tabarkiewicz J, Putowski LB. A Modified Method of Insulin Producing Cells ? Generation from Bone Marrow-Derived Mesenchymal Stem Cells. 2014;2014:1-7. doi:10.1155/2014/628591.
- Baglio SR, Rooijers K, Koppers-Lalic D, et al. Human bone marrow- and adipose-mesenchymal stem cells secrete exosomes enriched in distinctive miRNA and tRNA species. Stem Cell Res Ther. 2015;6(1):127. doi:10.1186/s13287-015-0116-z.
- am Esch JS, Knoefel WT, Klein M, et al. Portal application of autologous CD133+ bone marrow cells to the liver: a novel concept to support hepatic regeneration. Stem Cells. 2005;23(4):463-470. doi:10.1634/stemcells.2004-0283.
- Wang X, Nie S-P, Zhen L, et al. TCTAP A-156 Retrograde Coronary Vein Delivery of Basic Fibroblast Growth Enhances Bone Marrow Mesenchymal Stem Cells Engraftment for Myocardial Repair in a Canine Infarct Model. J Am Coll Cardiol. 2014;63(12):S44. doi:10.1016/j.jacc.2014.02.189.
- Al-sayegh H, Bashir J, Goodyear S, Freeman MD. A prospective multi-site registry study of a specific protocol of autologous bone marrow concentrate for the treatment of shoulder rotator cuff tears and osteoarthritis. 2015:269-276.
- Gabr MM, Zakaria MM, Refaie AF, et al. Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells into Insulin-Producing Cells?: Evidence for Further Maturation In Vivo. 2015;2015.
- Pai M, Zacharoulis D, Milicevic MN, et al. Autologous infusion of expanded mobilized adult bone marrow-derived CD34+ cells into patients with alcoholic liver cirrhosis. Am J Gastroenterol. 2008;103(8):1952-1958. doi:10.1111/j.1572-0241.2008.01993.x.
- Kushida T, Iida H. Bone marrow cell transplantation efficiently repairs tendon and ligament injuries. Front Cell Dev Biol. 2014;2(July):1-4. doi:10.3389/fcell.2014.00027.
- Schulte J, Knoefel T, Klein M, et al. Portal Application of Autologous CD133 + Bone Marrow Cells to the. 2005:463-470. doi:10.1634/stemcells.2004-0283.
- Scott M, Ph D, Marley SB, et al. Autologous Infusion of Expanded Mobilized Adult Bone Marrow-Derived CD34 + Cells Into Patients With Alcoholic Liver Cirrhosis. 2008:1952-1958. doi:10.1111/j.1572-0241.2008.01993.x.
- 2015 Murine Sca1+Lin? bone marrow contains an endodermal precursor population that differentiates into hepatocytes.pdf.
- Prabhakar S, Marwaha N, Lal V, Sharma RR, Rajan R, Khandelwal N. Autologous bone marrow-derived stem cells in amyotrophic lateral sclerosis: A pilot study. Neurol India. 2012;60(5):465-469. doi:10.4103/0028-3886.103185.
- Naaldijk Y, Jäger C, Fabian C, et al. Effect of systemic transplantation of bone marrow-derived mesenchymal stem cells on neuropathology markers in APP/PS1 Alzheimer mice. Neuropathol Appl Neurobiol. 2016:1-16. doi:10.1111/nan.12319.
- Nicola M Di, Carlo-stella C, Magni M, et al. induced by cellular or nonspecific mitogenic stimuli Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli. 2013;99(10):3838-3843. doi:10.1182/blood.V99.10.3838.
- Tzameret A, Sher I, Belkin M, et al. Epiretinal transplantation of human bone marrow mesenchymal stem cells rescues retinal and vision function in a rat model of retinal degeneration. Stem Cell Res. 2015;15(2):387-394. doi:10.1016/j.scr.2015.08.007.
- Augello A, Tasso R, Negrini SM, Cancedda R, Pennesi G. Cell therapy using allogeneic bone marrow mesenchymal stem cells prevents tissue damage in collagen-induced arthritis. Arthritis Rheum. 2007;56(4):1175-1186. doi:10.1002/art.22511.
- Capelli C, Domenghini M, Borleri G, et al. Human platelet lysate allows expansion and clinical grade production of mesenchymal stromal cells from small samples of bone marrow aspirates or marrow filter washouts. Bone Marrow Transplant. 2007;40(8):785-791. doi:10.1038/sj.bmt.1705798.
- Sanghi V, Sethi D, Harris KL, et al. International Journal of the Cardiovascular Academy Autologous bone marrow concentrate enriched in progenitor cells ? An adjuvant in the treatment of acute myocardial infarction. IJCAC. 2016. doi:10.1016/j.ijcac.2016.04.001.
- Oe K, Kushida T, Okamoto N, et al. New strategies for anterior cruciate ligament partial rupture using bone marrow transplantation in rats. Stem Cells Dev. 2011;20(4):671-679. doi:10.1089/scd.2010.0182.
- Ahmed HH, Salem AM, Atta HM, et al. Updates in the pathophysiological mechanisms of Parkinson?s disease: Emerging role of bone marrow mesenchymal stem cells. World J Stem Cells. 2016;8(3):106. doi:10.4252/wjsc.v8.i3.106.
- Cai J, Wu Z, Xu X, et al. Umbilical Cord Mesenchymal Stromal Cell With Autologous Bone Marrow Cell Transplantation in Established Type 1 Diabetes: A Pilot Randomized Controlled Open-Label Clinical Study to Assess Safety and Impact on Insulin Secretion. Diabetes Care. 2015:dc150171. doi:10.2337/dc15-0171.
- Abdel Aziz MT, Wassef MAA, Ahmed HH, et al. The role of bone marrow derived-mesenchymal stem cells in attenuation of kidney function in rats with diabetic nephropathy. Diabetol Metab Syndr. 2014;6(1):34. doi:10.1186/1758-5996-6-34.
- Al-sayegh H, Bashir J, Goodyear S, Freeman MD. A prospective multi-site registry study of a specific protocol of autologous bone marrow concentrate for the treatment of shoulder rotator cuff tears and osteoarthritis. 2015:269-276.
- Shabbir A, Zisa D, Suzuki G, Lee T. Heart failure therapy mediated by the trophic activities of bone marrow mesenchymal stem cells: a noninvasive therapeutic regimen. Am J Physiol Heart Circ Physiol. 2009;296(6):H1888-H1897. doi:10.1152/ajpheart.00186.2009.
- Collino F, Deregibus MC, Bruno S, et al. Microvesicles derived from adult human bone marrow and tissue specific mesenchymal stem cells shuttle selected pattern of miRNAs. PLoS One. 2010;5(7). doi:10.1371/journal.pone.0011803.
- Sanghi V, Sethi D, Harris KL, et al. International Journal of the Cardiovascular Academy Autologous bone marrow concentrate enriched in progenitor cells ? An adjuvant in the treatment of acute myocardial infarction. IJCAC. 2016. doi:10.1016/j.ijcac.2016.04.001.
- Fekete N, Rojewski MT, Fürst D, et al. GMP-compliant isolation and large-scale expansion of bone marrow-derived MSC. PLoS One. 2012;7(8). doi:10.1371/journal.pone.0043255.
- C. L, S.A. M, M. A, S.H. V, A. F-G. Exosomes mediate the cytoprotective effects of bone Marrow-Derived Stromal Cells (MSCS) on the hypoxic lung. Am J Respir Crit Care Med. 2011;183(1 MeetingAbstracts):no pagination. http://ajrccm.atsjournals.org/cgi/reprint/183/1_MeetingAbstracts/A3764?sid=f0b58cd0-9f08-401b-bb88-e9a3268d044f%5Cnhttp://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=reference&D=emed10&NEWS=N&AN=70848115.
- Islam MN, Das SR, Emin MT, et al. Mitochondrial transfer from bone-marrow-derived stromal cells to pulmonary alveoli protects against acute lung injury. Nat Med. 2012;18(5):759-765. doi:10.1038/nm.2736.
- Yoon SH, Shim YS, Park YH, et al. Complete spinal cord injury treatment using autologous bone marrow cell transplantation and bone marrow stimulation with granulocyte macrophage-colony stimulating factor: Phase I/II clinical trial. Stem Cells. 2007;25(8):2066-2073. doi:10.1634/stemcells.2006-0807.
- Hernigou P, Guissou I, Homma Y, et al. Percutaneous injection of bone marrow mesenchymal stem cells for ankle non-unions decreases complications in patients with diabetes. Int Orthop. 2015. doi:10.1007/s00264-015-2738-2.
- Davies OG, Smith AJ, Cooper PR, Shelton RM, Scheven BA. Cryobiology The effects of cryopreservation on cells isolated from adipose , bone marrow and dental pulp tissues q. Cryobiology. 2014;69(2):342-347. doi:10.1016/j.cryobiol.2014.08.003.
- C. L, S.A. M, M. A, S.H. V, A. F-G. Exosomes mediate the cytoprotective effects of bone Marrow-Derived Stromal Cells (MSCS) on the hypoxic lung. Am J Respir Crit Care Med. 2011;183(1 MeetingAbstracts):no pagination. http://ajrccm.atsjournals.org/cgi/reprint/183/1_MeetingAbstracts/A3764?sid=f0b58cd0-9f08-401b-bb88-e9a3268d044f%5Cnhttp://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=reference&D=emed10&NEWS=N&AN=70848115.
- Tang KX, Shen YF, Li BY, et al. Tracing type 1 diabetic Tibet miniature pig?s bone marrow mesenchymal stem cells in vitro by magnetic resonance imaging. J Diabetes. 2013;6:123-131. doi:10.1111/1753-0407.12084.
- Associates RM, Biosciences C. T RANSLATIONAL AND C LINICAL Percutaneous Injection of Autologous Bone Marrow Concentrate Cells Significantly Reduces Lumbar Discogenic Pain Through 12 Months. 2015:146-156.
- Kasahara Y, Matsuyama T, Taguchi A. Treatment of Autologous Bone Marrow Mononuclear Cells for Acute and Subacute Stroke Cell Therapy for Acute / Subacute Stroke. 2015:37-46. doi:10.1007/978.
- Qi X, Zhang J, Yuan H, et al. Exosomes secreted by human-induced pluripotent stem cell-derived mesenchymal stem cells repair critical-sized bone defects through enhanced angiogenesis and osteogenesis in osteoporotic rats. Int J Biol Sci. 2016;12(7):836-849. doi:10.7150/ijbs.14809.
- Shabbir A, Zisa D, Suzuki G, Lee T. Heart failure therapy mediated by the trophic activities of bone marrow mesenchymal stem cells: a noninvasive therapeutic regimen. Am J Physiol Heart Circ Physiol. 2009;296(6):H1888-H1897. doi:10.1152/ajpheart.00186.2009.
- Nicola M Di, Carlo-stella C, Magni M, et al. induced by cellular or nonspecific mitogenic stimuli Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli. 2013;99(10):3838-3843. doi:10.1182/blood.V99.10.3838.
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References and Literature - Stem Cell-based Therapies and Erectily dysfunction and impotence
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References and Literature - Stem Cell-based Therapies for Rheumatoid Arthritis
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