German Stem Cell Engineering:
The Science of a Better You
Stem cells are among your body’s basic building blocks. They are being investigated in research for a wide range of conditions, including age-related processes; their therapeutic potential is not yet established. Stem cell research has so far focused mainly on exploring possible medical applications, and the translation of these findings into established clinical practice is still at an early stage.
ANOVA Institute for Regenerative Medicine was founded to help bridge this gap between research and clinical practice, with a focus on translational medicine. We are a German medical institute that offers individualized treatments for patients. We employ licensed stem cell-based methods and apply strict safety and quality standards.
Stem Cell Therapies sorted by stem cell type (source tissue) and product
How Does the ANOVA Therapy Differ?
Diagnostics – We Look for the Cause of Your Pain
Dr. mult. Michael K. Stehling, the founder of ANOVA IRM and the Vitus Prostate Center , is a radiologist (MD) and holds a PhD in physics. For this reason, the ANOVA Institute for Regenerative Medicine, in cooperation with the Prof. Stehling Institute for Diagnostic Imaging located in the same building, has the capability to use special precision diagnostics such as arthro-MRI and non-radioactive contrast MRIs.
These imaging methods can help to localise inflammatory changes in the joints. This supports an individual assessment of how a patient may be treated and where a stem cell-based preparation would be applied.
Furthermore, in consultation with you, we supplement our patient-specific diagnostics with specific blood tests on hormones, inflammation parameters and other factors that are important in your case, or recommend further examinations such as a preventive MRI spinal scan.

Precision MRI scans - find the source of pain
ANOVA IRM © Siemens Healthcare GmbH
Contraindications
Our stem cell treatments are experimental, but we only treat patients for whom we believe the risk/benefit ratio indicates treatment based on the state of the art, i.e., medical, scientific evidence.
Please understand that we therefore do not treat patients for whom the following points apply:
- Active cancer in the last two years
- Not yet of legal age
- Existing pregnancy or lactation period
- Unable to breathe on own, ventilator
- Difficulty breathing in supine position
- Dysphagia (extreme difficulty swallowing)
- Psychiatric disorder
- Active infectious disease (Hepatitis A, B, C, HIV, Syphilis, or other)
The ANOVA Approach:
Image-Guided, Targeted Application of the Stem Cell Preparation
Stem cell injection into joints
ANOVA IRM Germany
Based on our specific diagnostics using arthro-MRI and non-radioactive contrast medium MRIs, we deliver the stem cell preparation with image support, e.g. using CT, targeted to the affected area. This allows the injection to be placed into and at the joint at the site where inflammation is causing pain; whether this results in a clinical effect cannot be predicted in the individual case. All interventions are performed under the supervision and care of our anaesthesiologist.
A purely intravenous administration, as many other clinics do, is only performed for the secretome (exosomes) if this is to be used additionally as a supportive or preventive measure because joint problems are present in several places in the body as laboratory and early clinical research is investigating whether the secretome can modulate immune responses.
Of course, we will thoroughly advise you in the early process and the on-site consultation in advance on all steps and discuss alternatives and expectations.
Are you Interested but Unsure?
Book a Counseling Appointment!
Our patient care managers are happy to inform you about what information we need upfront (MRI, CT, X-ray), how to transfer large data files and schedule a counseling appointment with our physicians for you. Please use our contact form to support a fast processing of your case and request.
You are also always welcome to send us an e-mail about your case. The counseling appointment may also take place per telephone or video chat if you live outside Germany. For more intense counseling or additional diagnostic evaluations you may also book an on-site appointment. We can perform needed MRI on the same day. All services rendered by our patient care team are free of charge and we inform you about all physician appointment charges up-front.

Stem cell-based treatment of the knee and hip joint
ANOVA IRM - Germany
German Stem Cell Engineering – Designed for your Needs
ANOVA offers the Stem Cell Secretome Therapy. Under a German manufacturing licence, we have developed a method that uses stem cells as a “factory” to produce the paracrine factors that stem cell research is currently investigating. Our manufacturing process is designed to follow defined quality standards; clinical experience with this approach is still early and limited.
Our regenerative medicine programs are applied in a range of conditions, from sports injuries to neurodegenerative diseases. Whether a stem cell-based therapy is an option in your individual case can only be assessed after a personal medical evaluation, and a treatment benefit cannot be promised. With our holistic approach we ensure that the focus lies on your individual needs.
If you have any questions regarding our stem cell-based therapies please feel free to give us a call or simply contact us by e-mail. ANOVA's specialists are looking forward to answering your questions on stem cells in detail. All cases are carefully evaluated on an individual basis by our Doctors and Scientists.
Schedule an appointment today: +49 (69) 50 50 00 944